Published Research
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Here are links to AOL research articles that were published in
international peer-reviewed journals.
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Naga Venkatesha Murthy, P.J., Gangadhar, B.N., Janakiramaiah, N., Subbakrishna, D.K. (1997).
Normalization of P300 Amplitude following Treatment in Dysthymia.
Biological Psychiatry, 42, 740-743.
 Abstract
Naga Venkatesha Murthy, P.J., Gangadhar, B.N., Janakiramaiah, N., Subbakrishna, D.K. (1997). Normalization of P300 Amplitude following Treatment in Dysthymia. Biological Psychiatry, 42, 740-743.
Studies in major depression have revealed “state” dependent smaller amplitude of P300 event related potential (ERP) (Blackwood et al 1987; Gangadhar et al 1993). Whether it is true in dysthymia remains untested.
In the study by Shagass et al (1985), neurotic patients were vaguely assumed to have a dysthymic disorder and the study included evoked potentials but not cognitive ERPs. Giese-Davis and Miller (1987) studied mismatched negativity in dysthymics (DYs), whereas Yee and Miller (1988) studied the emotional information processing with respect to modulation of fear, and did not address the P300 ERP abnormalities per se in DYs. Likewise, Yee et al (1992) have studied in DYs ERP components earlier to P300.
Bruder et al (1995) found reduced amplitude and hemispheric asymmetry of P300, using dichotic complex tone test, in 44 depressives (five DYs dysthymics). In the present study we compared the P300 ERP in DYs, depressives with melancholic features (DMs), normal controls, and included a follow-up to examine if P300 abnormalities persist upon improvement.
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Naga Venkatesha Murthy, P.J., Gangadhar, B.N., Janakiramaiah, N., Subbakrishna, D.K. (1997).
Normalization of P300 Amplitude following Treatment in Dysthymia.
Biological Psychiatry, 42, 740-743.
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Janakiramaiah, N., Gangadhar, BN., Naga Venkatesha Murthy, P.J., Harish, M.G., Subbakrishna D.K., Vedamurthachar A. (2000).
Antidepressant efficacy of Sudarshan Kriya Yoga (SKY) in melancholia: a randomized comparison with Electroconvulsive therapy (ECT) and Imipramine. Journal of Affective Disorders. 57(1-3):255-9.
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Bhatia, M., Kumar, A., Kumar, N., Pandey, R.M., and Kochupillai, V. (2003).
Electrophysiologic evaluation of Sudarshan Kriya: an EEG, BAER, and P300 study. Indian J. Physiol. Pharmacol. 47, 157-163.
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Sharma, H., Sen, S., Singh, N.K. Bhardwaj, V. Kochupillai, N. Singh (2003).
Sudarshan Kriya practitioners exhibit better antioxidant status and lower blood lactate levels. Biological Psychology 63:281-291.
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Gerbarg, P.L., and Brown, R.P. (Oct. 2005).
Yoga: A breath of relief for Hurricane Katrina refugees. Current Psychiatry 4, 55-67.
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Kochupillai, V., Kumar, P., Singh, D., Aggarwal, D., Bhardwaj, N., Bhutani, M., DAS, S.N. (2005)
Effect of rhythmic breathing (sudarshan kriya and pranayam) on immune functions and tobacco addiction. Ann N Y Acad Sci. 1056:242-52.
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Vedamurthachar, A., Janakiramaiah, N., Hegde, J.M., Shetty, T.K., Subbakrishna, D.K., Sureshbabu, S.V., Gangadhar, B.N. (2006)
Antidepressant efficacy and hormonal effects of Sudarshan Kriya Yoga (SKY) in alcohol dependent individuals. J Affect Disord. 94, 249-253.
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Brazier, A., Mulkins, A., Verhoef, M. (2006)
Evaluating a yogic breathing and meditation intervention for individuals living with HIV/AIDS. Am J Health Promot. 20, 192-195.
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Sageman, S., and Brown, R. 2006.
Free at Last, in DSM-IV-TR Case Book Volume 2, edited by R.L. Spitzer, M.B. First, J.B.W.Williams, M. Gibbon. American Psychiatric Publishing, Inc. Washington, DC. 2006. pp.109-121.
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Kjellgren, A, Bood, SA, Axelsson, K, Norlander, T, Saatcioglu, F.(2007).
Wellness through a comprehensive Yogic breathing program - A controlled pilot trial. BMC Complement Altern Med. 7:43-50
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Sharma H, Datta P, Singh A, Sen S, Bhardwaj NK, Kochupillai V, Singh N. (2008)
Gene expression profiling in practitioners of Sudarshan Kriya. J Psychosom Res. 2008 Feb;64(2):213-8
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Descilo, T., Vedamurtachar. A., Gerbarg, P. L., Nagaraja, D., Gangadhar, B. N., Damodaran, B., Adelson, B., Braslow, L. H., Marcus, S., Brown, R. P. (2009).
Effects of a yoga breath intervention alone and in combination with an exposure therapy for post-traumatic stress disorder and depression in survivors of the 2004 South-East Asia tsunami. Acta Psychiatr Scand., in press.
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Gootjes, L., Franken, I.H.A., and Van Strien, J.W. (2011) Cognitive emotion regulation in yogic meditative practitioners - Sustained modulation of electrical brain potentials.
Journal of Psychophysiology 2011; Vol. 25(2):87-94
Abstract
Gootjes, L., Franken, I.H.A., and Van Strien, J.W. (2011) Cognitive emotion regulation in yogic meditative practitioners - Sustained modulation of electrical brain potentials.
Recently, there is a growing interest in meditation as an attentional and emotional regulatory strategy. To examine whether meditative practice is associated with successful emotion regulation, we examined the neurophysiological correlates of cognitive reappraisal in practitioners of a yogic meditative technique and controls.
Participants were presented aversive pictures and were asked to cognitively change their appraisal of the affective meaning of the pictures by coming up with an alternative more positive interpretation of each picture. We found reduced magnitude of Event-Related Potentials (P300 and early time intervals of the late positive potential, LPP) following cognitive reappraisal of aversive pictures in both groups. However, in the yogic group, reduced magnitude was sustained during the later intervals of the LPP, while it subsided in the control group. Moreover, reduced amplitude of the late LPP correlated positively with experience of the technique.
Results suggest a relation between yogic meditative practice and sustained attenuation of emotional response following emotion regulation. Increased positive affect and familiarity with cognitive emotion regulation in the yogic group may explain this effect. Whether this is a direct causal effect of the practice or can be attributed to characteristics of the participants that preexisted the training needs further examination in a randomized longitudinal study.
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